Cancer is a disease that affects millions of families around the world, treating all the same be it someone young or old, or someone rich or poor. There are different forms of cancer and one that is rising at an alarming rate is breast cancer.
BRCA refers to breast cancer, which is usually classified into Breast cancer type 1 and Type 2. There are two genes, namely, BRCA1 and BRCA2 which are found in every normal individual. But any genetic variation or mutations occurring in either of these two genes, can lead to the incidence of breast and ovarian cancer.
How is a BRCA mutation inherited? Mutations in the BRCA1 and BRCA2 genes are inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to increase a person's chance of developing cancer. Although breast cancer is more common in women than in men, the mutated gene can be inherited from either the mother or the father. But, not all breast cancers are inherited. These cancers are acquired during a person's lifetime, and they do not cluster in families.
About Genes2Me offering for BRCA mutation screening Genes2Me offer a thorough screening of BRCA1 and BRCA2 mutations, which helps in identifying the clinically relevant or pathogenic mutations. Our panel of breast cancer screening covers most of the reported and commonly occurring mutations. Screening is performed on a high end and sophisticated platform of Next generation sequencing (NGS) technique. Regular screening aids early diagnosis, which provides a bigger room for complete cure of breast or ovarian cancer. Reporting of findings is done only for clinically relevant mutations with >100x coverage.
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